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Clinical trials

Clinical trials conducted to evaluate the efficacy and safety of Nasodren® in the treatment of sinusitis have been published in the most rigorous, wide-reaching scientific journals, including Rhinology, the official journal of the European Rhinologic Society, and The Laryngoscope, the official journal of the American Rhinologic Society.

Cyclamen europaeum improves the effect of oral antibiotics on exacerbations and recurrences of chronic rhinosinusitis: a real-life observational study (CHRONOS)
2017
A clinical study on the use of Sinuforte® as initial monotherapy for acute rhinosinusitis, associated with exudative otitis media, in children and adolescents
2013
Pharmacoeconomics of Cyclamen europaeum in the Management of Acute Rhinosinusitis
2013
An Exploratory Trial of Cyclamen europaeum Extract for Acute Rhinosinusitis
2012
Cyclamen europaeum nasal spray, a novel phytotherapeutic product for the management of acute rhinosinusitis: a randomized double-blind, placebo-controlled trial
2012
Medicamental rhinitis. New possibilities for its conservative treatment
2012
Specific microendoscopic characteristics of intranasal mucosa in patients presenting with chronic rhinosinusitis and treated with Sinuforte®
2011
Use of Sinuforte® in national and international practice
2010
Comparative evaluation of various conservative treatment methods for exudative rhinosinusitis
2010
A New Method of Conservative Residual OME Treatment
2010
Assessment of the effectiveness of Sinuforte® (extract of Cyclamen) used for the combined treatment of rhinosinusitis and exudative otitis media in children
2010
Efficacy of Sinuforte® in the treatment of patients with acute purulent rhinosinusitis
2009
Trends on Rhinosinusitis Diagnosis and Treatment
2009
A secretion stimulant with anti‐edema action in the treatment of acute rhinosinusitis
2008
Effect of Sinuforte® on quality of life of patients with sinusitis
2008
An alternative, non‐invasive therapy for acute sinusitis
2008
Quantitative histological and histochemical study of the reaction of the nasal cavity and maxillary sinus glands to contact with Sinuforte®
2008
New approaches to the non­‐invasive therapy of rhinosinusitis in adolescents
2008
Dynamics of the transport and heating function indices of the mucous membrane of the nasal cavity in the early postoperative management of patients with chronic rhinosinusitis
2007
Objective Assessment of the Efficacy of Secretion-dissolving, Secretion-stimulating Treatment in Multimodal Therapy for Acute Rhinosinusitis Cases
2007
New perspectives in non-invasive treatment of sinusitis
2007
Influence of Sinuforte® on nasal mucosa microcirculation
2007
Study of efficacy of Sinuforte® monotherapy in patients with acute and chronic rhinosinusitis at an exacerbation stage
2007
Reflex mechanisms of nasoparanasal secretion in the administration of Sinuforte®
2007
Use of Sinuforte® in the management of acute rhinosinusitis and secretory otitis in children
2006
Treatment of exudative otitis media with Sinuforte®
2004
Clinical investigation of the efficacy of the use of a new plant-based product in children with acute rhinosinusitis
2004
Use of a new plant extract-based product in acute purulent rhinosinusitis
2004
Use of a new plant extract-based product in inflammatory diseases of the paranasal sinuses
2003
Treatment of acute purulent sinusitis with Sinuforte®
2003
Efficacy of Sinuforte® for the treatment of sinusitis patients
2002

*Sinuforte® is another brand name for the nasal spray made from Cyclamen extract.

Nasodren® is a 100% natural, effective and safe spray for the relief of all the symptoms of sinus infection. Quick relief from the first application.

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